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Reminds me of my childhood in the 70's around the London dockyards. Many friends lost to drugs and glue (we called em glue-sniffers but was any type of solvent, tippex thinners was popular). These kids abuse until their upper palette collapses and they suffocate, you can hear it coming in their slurred speech and constant spitting of 'greenies'. Despite it all, I still feel the worst is alcohol abuse.Not my work but a pretty dramatic insight into Bangkok's back streets and some quite superb images.
http://www.ckphoto.eu/Bangkok%20Dreams%20SS/