I used to have and very much liked the XT-2 which was a small form factor AF camera with small lenses too. I am thinking that pairing the XT-5 with the new 56/1.2 could be about the perfect portrait lens combo. Cannot believe the XT-5 will be priced at the same $1699. as the XT-2 was priced many years ago.
Now with Topaz AI one can enlarge a cropped sensor image when needed for larger printing, say 17x22.
I assume you mean 17x22 inches, and not centimetres?
I regularly print at 24x16 inches and even 30x20 with the X-T3 and X-T4 and I don't have any problems with image quality. Even frames at iso12800. I now use DxO PureRAW2 but before I would use TopazAI Denoise/Sharpen if I felt the image needed additional post processing for noise or sharpness.
I'm not saying the X-T5 won't be an awesome camera and at some point I will probably get one, just that you can already print at those sizes with the existing sensors, in my experience.
Actually, I also print at 24x16 inches with my Ricoh GRIII and in some cases, especially a couple of times when I've shot the X-T3 and GRIII side by side (not done it with the X-T4 as it is the same sensor as the X-T3), I've got better printed results with the Ricoh.
Now, you got me thinking. A Ricoh GRIV with a 40mpx sensor! Awesome!
Just my two cents.
LouisB